Blar i forfatter "Moyo, Sabrina John"
-
Capture of a novel, antibiotic resistance encoding, mobile genetic element from Escherichia coli using a new entrapment vector
Tansirichaiya, Supathep; Moyo, Sabrina John; Al-Haroni, Mohammed; Roberts, Adam P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-01)<b><p>Aims</b> Antimicrobial resistance genes (ARGs) are often associated with mobile genetic elements (MGEs), which facilitate their movement within and between bacterial populations. Detection of mobility is therefore important to understand the dynamics of MGE dissemination and their associated genes, especially in resistant clinical isolates that often have multiple ARGs associated with MGEs. ... -
Horizontal plasmid transfer among klebsiella pneumoniae isolates is the key factor for dissemination of extended-spectrum β-lactamases among children in Tanzania
Pedersen, Torunn Annie; Tellevik, Marit Gjerde; Kommedal, Øyvind; Lindemann, Paul Christoffer; Moyo, Sabrina John; Janice, Jessin; Blomberg, Bjørn; Samuelsen, Ørjan; Langeland, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-15)Increased knowledge about the role of horizontal gene transfer is key to improve our understanding of the spread of antimicrobial resistance (AMR) in human populations. We therefore studied the dissemination of the <i>bla</i><sub>CTX-M-15</sub> extended-spectrum-β-lactamase (ESBL) gene in <i>Klebsiella pneumoniae</i> isolates obtained from stool samples from hospitalized children and healthy controls ... -
Identification of VIM-2-producing Pseudomonas aeruginosa from Tanzania is associated with sequence types 244 and 640 and the location of blaVIM-2 in a TniC integron
Moyo, Sabrina John; Haldorsen, Bjørg; Aboud, Said; Blomberg, Bjørn; Maselle, Samuel Y; Sundsfjord, Arnfinn; Langeland, Nina; Samuelsen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Plasma parasitemia as assessed by quantitative PCR in relation to clinical disease severity in African adults with falciparum malaria with and without HIV co-infection
Berg, Åse; Patel, Sam; Tellevik, Marit Gjerde; Haanshuus, Christel Gill; Dalen, Ingvild; Otterdal, Kari; Ueland, Thor; Moyo, Sabrina John; Aukrust, Pål; Langeland, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-19)<p><i>Purpose - </i>When considering malaria disease severity, estimation of parasitemia in erythrocytes is important, but sometimes misleading, since the infected erythrocytes may be sequestered in peripheral capillaries. In African children and Asian adults with falciparum malaria, parasitemia as assessed by quantitative PCR (qPCR) in plasma seems to be a valuable indicator of disease severity, ... -
Use of probiotics to reduce infections and death and prevent colonization with extended-spectrum beta-lactamase (ESBL)-producing bacteria among newborn infants in Tanzania (ProRIDE Trial): study protocol for a randomized controlled clinical trial
Kuwelker, Kanika; Langeland, Nina; Löhr, Iren Høyland; Gidion, Joshua; Manyahi, Joel; Moyo, Sabrina John; Blomberg, Bjørn; Klingenberg, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-29)<i>Background</i> - Extended-spectrum beta-lactamase-producing <i>Enterobacteriaceae</i> (ESBL-E) has emerged as an urgent global health threat and is by the World Health Organization ranked as priority 1 among pathogens in need of new treatment. Studies have shown high mortality in Tanzanian children with ESBL-E infections. Gut colonization of ESBL-E, which is a potential risk factor of ESBL-E ...